The Equilibrium Constants of the Adenosine Triphosphate Hydrolysis and the Adenosine Triphosphate-Citrate Lyase Reactions
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چکیده
منابع مشابه
The equilibrium constants of the adenosine triphosphate hydrolysis and the adenosine triphosphate-citrate lyase reactions.
The observed standard free energy change (AGibs) for the hydrolysis of the terminal pyrophosphate bond of ATP has been experimentally determined under physiological conditions using an entirely new set of reactions. The observed equilibrium constant (K,,bs) for the combined reactions of acetate kinase (EC 2.7.2.1) and phosphate acetyltransferase (EC 2.3.1.8) has been determined at 38”, pH 7.0, ...
متن کاملThe Eq+librium Constants of the Adenosine Triphosphate Hydrolysis and the Adenosine Triphosphate- Citrate Lyase Reactions
The observed standard free energy change (AGibs) for the hydrolysis of the terminal pyrophosphate bond of ATP has been experimentally determined under physiological conditions using an entirely new set of reactions. The observed equilibrium constant (K,,bs) for the combined reactions of acetate kinase (EC 2.7.2.1) and phosphate acetyltransferase (EC 2.3.1.8) has been determined at 38”, pH 7.0, ...
متن کاملAdenosine Triphosphate Citrate Lyase in Hypocitraturia
Chronic metabolic acidosis increases proximal tubular citrate uptake and metabolism. The present study addressed the effect of chronic metabolic acidosis on a cytosolic enzyme of citrate metabolism, ATP citrate lyase. Chronic metabolic acidosis caused hypocitraturia in rats and increased renal cortical ATP citrate lyase activity by 67% after 7 d. Renal cortical ATP citrate lyase protein abundan...
متن کاملAdenosine triphosphate citrate lyase mediates hypocitraturia in rats.
Chronic metabolic acidosis increases proximal tubular citrate uptake and metabolism. The present study addressed the effect of chronic metabolic acidosis on a cytosolic enzyme of citrate metabolism, ATP citrate lyase. Chronic metabolic acidosis caused hypocitraturia in rats and increased renal cortical ATP citrate lyase activity by 67% after 7 d. Renal cortical ATP citrate lyase protein abundan...
متن کاملEquilibrium constants of the reactions of acetyl coenzyme A synthetase and the hydrolysis of adenosine triphosphate to adenosine monophosphate and inorganic pyrophosphate.
The observed standard free energy change (AGtbs) for the ATP-pyrophosphorylase reaction (EC 3.6.1.8) has been calculated for near physjological conditions of temperature, ionic strength, and free magnesium concentration. The observed equilibrium constant (Kobs) for the acetyl-CoA synthetase reaction (EC 6.2.1.1) has been determined at both 25 and 38”, pH 7.0, ionic strength 0.25, and varying fr...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1973
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)43347-4